Twitter is becoming one of the fastest growing social networks with a growth rate of more than 55 % per month. More 
than hundreds of different applications have been developed for a better usage of Twitter.
Twitter has been mentioned almost anywhere and even big corporations or celebrities are using Twitter. A good idea would be to open micro-niche blogging sites just like Twitter, but focused on a specific niche.
Open Source Twitter Clones
Actually there exist a couple of twitter clones but the most interesting version which I would definitely give a go is Laconica
Laconica (pronounced “luh-KAWN-ih-kuh”) is a Free and Open Source microblogging platform. It helps people in a community, company or group to exchange short (140 character) messages over the Web. Users can choose which people to “follow” and receive only their friends’ or colleagues’ status messages. It provides a similar service to sites like Twitter, Jaiku, and Plurk.
For more information and or the download link you can visit Laconica
You can also check a live example of how the Laconica script looks and functions over at Identi.ca, which is the official site which uses the twitter clone script made by Laconica
A Twitter like site, designed particularly for a specific niche can go viral immediately and the potential actually is quite big. Once you set it up properly, you only have to market it all over the internet (no spam) and you gonna see some activity on your own twitter clone site
Category: Webmaster
Thanks man,I have beign looking for a script like this.
Interesting! I’d have to check Laconica out and see what it’s all about. Thanks for the heads up!
Hmmm…a twitter clone site. Pretty interesting!!!Thanks for sharing about this.
So nice site. I will visit it more often and read comments. Thx u a lot